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We plan to start a cohort of MCLA-129 in combination with chemotherapy in 2L+ EGFRm NSCLC in the 1st quarter of future year. Furthermore, we continue to be interested and therefore are continuing investigation of cohort B evaluating MCLA-129 in patients with Achieved exon14 skipping NSCLC. We also continue being keen on Discovering partnering MCLA-129 with other organizations to adequately useful resource the event of MCLA-129 and source likely advantage it may have for people.
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Our assessment of this cohort is that the clinical activity of MCLA-129 in second line head and neck cancer appears significantly inferior to that of our guide asset petosemtamab, and only on par with other EGFR or cetuximab-based monoclonal or bispecific antibodies as monotherapy in a similar location. We consider this efficacy is insufficient to warrant more improvement in head and neck cancer.
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